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DiscoveryProbe™ TGF-beta/Smad Compound Library
A unique collection of 60 TGF-beta/Smad inhibitors for TGF-beta/Smad signaling pathway research.

Catalog No.L1045
Size Price Stock Qty
100uL/well(10 mM solution)
$1,370.00
In stock
250uL/well(10 mM solution)
$2,440.00
In stock
5mg/well
$3,190.00
In stock

Tel: +1-832-696-8203

Email: [email protected]

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Sample solution is provided at 25 µL, 10mM.

Click and Customize the Panel with your own choices of compounds/size/quantities/chemical forms etc.

HTS Facility Partners

HTS Facility Partners

Featured Products of the Library

Catalog No. Product Name Summary Targets CAS Number Smiles
A1670 Enzastaurin (LY317615) PKC beta inhibitor,potent and selective PKC 170364-57-5 CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7
A1805 Imatinib Mesylate (STI571) Abl/c-kit/PDGFR inhibitor Bcr-Abl 220127-57-1 CC1=C(C=C(C=C1)NC(=O)C2=CC=C(C=C2)CN3CCN(CC3)C)NC4=NC=CC(=N4)C5=CN=CC=C5.CS(=O)(=O)O
A2133 Saracatinib (AZD0530) Src/Abl inhibitor,potent and selective Bcr-Abl 379231-04-6 CN1CCN(CC1)CCOC2=CC(=C3C(=C2)N=CN=C3NC4=C(C=CC5=C4OCO5)Cl)OC6CCOCC6
A3008 Y-27632 dihydrochloride ROCK1 inhibitor ROCK 146986-50-7;129830-38-2 CC(C1CCC(CC1)C(=O)NC2=CC=NC=C2)N
A5602 SB525334 (TGF-beta1) receptor inhibitor TGF-βR1(ALK5) 356559-20-1 CC1=CC=CC(=N1)C2=C(N=C(N2)C(C)(C)C)C3=CC4=NC=CN=C4C=C3
A8249 SB 431542 ALK inhibitor TGF-βR1(ALK5) 301836-41-9 C1OC2=C(O1)C=C(C=C2)C3=C(NC(=N3)C4=CC=C(C=C4)C(=O)N)C5=CC=CC=N5
A8342 GF 109203X Protein kinase C,MLCK,PKG and PKA inhibitor PKC 133052-90-1 CN(C)CCCN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
A8348 LY2157299 TGF-βR1 inhibitor,potent and selective TGF-βR1(ALK5) 700874-72-2 CC1=CC=CC(=N1)C2=NN3CCCC3=C2C4=C5C=C(C=CC5=NC=C4)C(=O)N
Download the TGF-beta-Smad-Compound-Library - XLSX       Download the TGF-beta-Smad-Compound-Library - SDF

Quality Control

Related Biological Data

Enzastaurin (LY317615)

Related Biological Data

Enzastaurin (LY317615)

Related Biological Data

Y-27632

Related Biological Data

Nilotinib

Related Biological Data

Nilotinib

Signaling Pathway

Bcr-Abl Compare Products
TGF-βR1(ALK5) Compare Products
ROCK Compare Products

Advantages

  • Available in stock with overnight delivery and free shipping over $500
  • Cost-effective and competitive price to save your findings
  • Potent, selective and cell-permeable in inhibiting or activating target molecules
  • Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
  • Detailed files describing potency, selectivity and applications etc.
  • Supported by published data from top peer-reviewed journals
  • Guaranteed high quality with NMR and HPLC validation

Storage and Shipping Information

Form Pre-dissolved DMSO solutions Stability -20°C: 12 months
-80°C: 24 months
Packaging 96 Well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.
General tips For obtaining a higher solubility , please warm the tube at 37°C and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20°C for several months.
Shipping Condition Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request

Compound Library Composition