Amoxicillin trihydrate
Amoxicillin trihydrate is a penicillin-structural similar to ampicillin and broad spectrum antibiotic [1].
Amoxicillin trihydrate has shown an antibacterial spectrum comparable to that of ampicillin and be better absorbed after oral administration. In addition, the antibacterial activity of Amoxicillin trihydrate against approximately 30 isolates each of Escherichia coli, Proteus mirabilis, Kiebsiella, Enterobacter, andindole-positive Proteus specie with the MIC values of 0.01μg/ml, 0.25μg/ml and 50μg/ml for Str.viridans, Bacillus anthracis and P.rettgeri, respectively. Apart from these, Amoxicillin trihydrate has been found to produce substantially higher serum levels than the same dose of ampicillin [1,2,3].
References:
[1] H. Hunter Handsfield, Hugh Clark, James F. Wallace, King K. Holmes and Marvin Turck Amoxicillin, a New Penicillin Antibiotic
[2] Bodey GP, Nance J. Amoxicillin: in vitro and pharmacological studies. Antimicrob Agents Chemother. 1972 Apr;1(4):358-62.
[3] Bodey GP, Nance J. Amoxicillin: in vitro and pharmacological studies. Antimicrob Agents Chemother. 1972 Apr;1(4):358-62.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 419.45 |
| Cas No. | 61336-70-7 |
| Formula | C16H25N3O8S |
| Solubility | insoluble in H2O; insoluble in EtOH; ≥14.8 mg/mL in DMSO |
| Chemical Name | (2S,5R,6S)-6-((S)-2-amino-2-(4-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate |
| SDF | Download SDF |
| Canonical SMILES | N[C@H](C(N[C@H]1C(N2[C@@H]1SC(C)(C)[C@@H]2C(O)=O)=O)=O)C3=CC=C(O)C=C3.O.O.O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
