Anti-Argonaute 2 Rabbit Monoclonal Antibody
Catalog No.
MA1300
Anti-Argonaute 2 Rabbit Monoclonal Antibody
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Required for RNA-mediated gene silencing (RNAi) by the RNA-induced silencing complex (RISC). Can also upregulate the translation of specific mRNAs under certain growth conditions. Binds to the AU element of the 3'-UTR of the TNF (TNF-alpha) mRNA and upregulates translation under conditions of serum starvation. Also required for transcriptional gene silencing (TGS), in which short RNAs known as antigene RNAs or agRNAs direct the transcriptional repression of complementary promoter regions.
27161
Ago 2; Argonaute 2; dAgo2; eIF2C 2; hAgo2; PPD
Rabbit
Human, Mouse, Rat
Unconjugated
Calculated MW: 97 kDa
Unmodified
IgG
Monoclonal Antibody
AP-7C5F11
Liquid
See label
Carrier Free
A synthesized peptide derived from human Argonaute 2
Affinity Chromatography
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
WB, IHC-P, ICC/IF, FC, IP
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.