Anti-Cyclin E2 Rabbit Monoclonal Antibody
Catalog No.
MA2110
Anti-Cyclin E2 Rabbit Monoclonal Antibody
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The human Cyclin E2 gene encodes a 404 amino acid protein that is most closely related to Cyclin E. Cyclin E2 mRNA levels peaks at the G1 / S transition. Cyclin E2 associates with Cdk2 in a functional kinase complex that is inhibited by both p27 (Kip1) and p21 (Cip1). Cyclin E2 / Cdk2 phosphorylates histone H1 in vitro. G1 cyclin E controls the initiation of DNA synthesis by activating CDK2. Abnormally high levels of cyclin E expression have frequently been observed in human cancers.
9134
CCNE2; G1/S-specific cyclin-E2
Rabbit
Human
Unconjugated
Calculated MW: 47 kDa; Observed MW: 47 kDa
Unmodified
IgG
Monoclonal Antibody
AP-1H1A3
Liquid
See label
Carrier Not Free
A synthetic peptide of human Cyclin E2
Affinity Purified
50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA.
WB, IHC-F, IHC-P, ICC/IF
Blue ice
-20°C
12 months
Please avoid freeze-thaw cycles.