Anti-Inflammatory Peptide 1
Anti-Inflammatory Peptide 1 (C45H82N12O14S2), with the sequence H-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH, belongs to the group of synthetic oligopeptides corresponding to a region of high amino-acid sequence similarity between uteroglobin and lipocortin I. The name 'antiflammins' is proposed for those peptides, which are valuable models for the development of novel anti-inflammatory agents of therapeutic importance. Anti-inflammatory peptide 1 possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammation and pain at certain bodily sites.
Ref:
1. Argiolas A, Pisano JJ (November 1983). "Facilitation of phospholipase A2 activity by mastoparans, a new class of mast cell degranulating peptides from wasp venom". J. Biol. Chem. 258 (22): 13697–702.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 1079.33 |
| Cas No. | 118850-71-8 |
| Formula | C45H82N12O14S2 |
| Synonyms | H2N-Met-Gln-Met-Lys-Lys-Val-Leu-Asp-Ser-OH |
| Solubility | ≥107.9 mg/mL in DMSO; insoluble in EtOH; ≥21.13 mg/mL in H2O |
| Chemical Name | Anti-Inflammatory Peptide 1 |
| SDF | Download SDF |
| Canonical SMILES | CC(C)CC(C(=O)NC(CC(=O)O)C(=O)NC(CO)C(=O)O)NC(=O)C(C(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCCN)NC(=O)C(CCSC)NC(=O)C(CCC(=O)N)NC(=O)C(CCSC)N |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
