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Anti-Siglec-3/CD33 Antibody (LintuzumAb)

Catalog No.
F1168
Anti-Siglec-3/CD33 Antibody (LintuzumAb)
Grouped product items
SizePriceStock Qty
100ug
$50.00
Ship with 3-5 days
1mg
$136.00
Ship with 3-5 days
5mg
$352.00
Ship with 3-5 days
50mg
$1,441.00
Ship with 3-5 days
For scientific research use only and should not be used for diagnostic or medical purposes.

Tel: +1-832-696-8203

Email: [email protected]

Worldwide Distributors

Background

Lintuzumab (HUM-195) is an anti-CD33 humanized monoclonal antibody. Lintuzumab reduces TNFα-induced proinflammatory cytokine and chemokine production by AML cells. Lintuzumab exerts tumor cell killing effects on MDR? and MDR+ AML cell lines and primary AML patient samples through antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis (ADCP) activities. Lintuzumab improves the survival rate of tumor-bearing mice and reduces tumor burden.

Quality Control

Quality Control & DataSheet

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M.Wt

145 kDa

Shipping

Dry ice

Cas No.

166089-32-3

Storage

-80°C

Expiration Date

2 years

Form

Liquid

Concentration

See label

Reconstitution

For reconstitution, we recommend adding sterile, distilled water to achieve a final antibody concentration. Gently shake it to solubilize the protein completely. Do not vortex.

Host

CHO

Alternative Names

SGN-33, HuM195, Actimab-A

Buffer System

100 mM Pro 20 mM Arg pH 5.0. No preservative!

Target Accession

O14793

Reactivity

Human

Conjugation

Unconjugated

Clonality

Monoclonal

Purification

Protein A

Isotype

IgG1

Application

ELISA, FACS, Kinetics, Functional assay, Animal Model

Target

GDF8 / Myostatin

Note

Please avoid freeze-thaw cycles.