BAY1161909
Catalog No.
B8450
Featured Products
BAY1161909 is an oral bioavailable selective inhibitor of serine / threonine monopolar spindle 1 (Mps1) kinase with potential antitumor activity. After administration, BAY1161909 binds and inhibits the activity of Mps1, leading to inactivation of spindle assembly checkpoints (SAC), accelerated mitosis, chromosomal misalignment, chromosomal mispolymerization, unstable mitotic checkpoint complexes and increased aneuploidy . This leads to the induction of cell death in cancer cells that overexpress Mps1.
| Storage | Store at -20°C |
| M.Wt | 559.61 |
| Cas No. | 1443763-60-7 |
| Formula | C29H26FN5O4S |
| Synonyms | Empesertib |
| Solubility | ≥35 mg/mL in DMSO |
| Chemical Name | (R)-2-(4-fluorophenyl)-N-(4-(2-((2-methoxy-4-(methylsulfonyl)phenyl)amino)-[1,2,4]triazolo[1,5-a]pyridin-6-yl)phenyl)propanamide |
| SDF | Download SDF |
| Canonical SMILES | FC1=CC=C([C@H](C(NC2=CC=C(C3=CN4N=C(N=C4C=C3)NC5=CC=C(S(=O)(C)=O)C=C5OC)C=C2)=O)C)C=C1 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
