Beclomethasone dipropionate
Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis [1].
Beclomethasone dipropionate(BDP) is a topically active and anti-inflammatory corticosteroid used in treatment of asthma and rhinitis. In addition, Beclomethasone dipropionate has been reported to be previously developed as aqueous nasal formulations for the treatment of Allergic rhinitis. Moreover, Beclomethasone dipropionate has shown the availability in dry nasal aerosol formulations as chiorofluoro carbon metered-dose inhaler nasal sprays [1].
References:
[1] Ratner PH1, Melchior A, Dunbar SA, Tantry SK, Dorinsky PM. Pharmacokinetic profile of beclomethasone dipropionate hydrofluoroalkane after intranasal administration versus oral inhalation in healthy subjects: results of a single-dose, randomized, open-label, 3-period crossover study. Clin Ther. 2012 Jun;34(6):1422-31.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 521.04 |
| Cas No. | 5534-09-8 |
| Formula | C28H37ClO7 |
| Solubility | insoluble in H2O; ≥12.72 mg/mL in EtOH with ultrasonic; ≥16.95 mg/mL in DMSO |
| Chemical Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate |
| SDF | Download SDF |
| Canonical SMILES | CCC(=O)OCC(=O)C1(C(CC2C1(CC(C3(C2CCC4=CC(=O)C=CC43C)Cl)O)C)C)OC(=O)CC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
