Cyclic di-GMP
Catalog No.
B7839
second messenger
Featured Products
Cyclic-di-GMP is a STING agonist and a ubiquitous second messenger that regulates biofilm formation, motility, and virulence in diverse bacterial species.
References :
[1]. Nakamura T, et al. Liposomes loaded with a STING pathway ligand, cyclic di-GMP, enhance cancer immunotherapy against metastatic melanoma. J Control Release. 2015 Oct 28;216:149-57.
[2]. Burdette DL, et al. STING is a direct innate immune sensor of cyclic di-GMP. Nature. 2011 Sep 25;478(7370):515-8.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 690.41 |
| Cas No. | 61093-23-0 |
| Formula | C20H24N10O14P2 |
| Solubility | insoluble in DMSO; insoluble in EtOH; ≥20.85 mg/mL in H2O |
| Chemical Name | 9,9'-((2R,3R,3aS,7aR,9R,10R,10aS,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidodecahydrodifuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl)bis(2-amino-1H-purin-6(9H)-one) |
| SDF | Download SDF |
| Canonical SMILES | O=C1NC(N)=NC2=C1N=CN2[C@H](O[C@@]([C@@]3([H])OP(O)(OC[C@]([C@@]4([H])OP5(O)=O)(O[C@@H](N6C(N=C(N)NC7=O)=C7N=C6)[C@@H]4O)[H])=O)(CO5)[H])[C@@H]3O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
- Datasheet
Chemical structure
