Dibucaine
Catalog No.
B3373
Local anesthetic
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Dibucaine is an amin amide local anesthetic [1].
Dibucaine has shown the ability to block the fast axonal transport of proteins. In addition, a 0.5 mM concentration of Dibucaine has been revealed to inhibit transport approximately as much as dose a 1mM concentration of tetracaine. Furthermore, 1mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 92%, and 0.5mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 72% in the experiments examined the effect on fast axonal transport of 3H-proteins [1].
References:
[1] Lavoie PA. Block of fast axonal transport in vitro by the local anesthetics dibucaine and etidocaine. J Pharmacol Exp Ther. 1982 Oct;223(1):251-6.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 343.46 |
| Cas No. | 85-79-0 |
| Formula | C20H29N3O2 |
| Solubility | insoluble in H2O; ≥16.45 mg/mL in DMSO; ≥27.1 mg/mL in EtOH |
| Chemical Name | 2-butoxy-N-[2-(diethylamino)ethyl]quinoline-4-carboxamide |
| SDF | Download SDF |
| Canonical SMILES | CCCCOC1=NC2=CC=CC=C2C(=C1)C(=O)NCCN(CC)CC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
