DiscoveryProbe™ Clinical & FDA approved Drug Library
Catalog No.
L1052
A collection of 2726 clinical & FDA approved drugs supplied as lyophilized powder or pre-dissolved DMSO solutions
Featured Products
- 1. Yushu Ma, Chien-Hung Shih, et al. "High-Throughput Empirical and Virtual Screening to Discover Novel Inhibitors of Polyploid Giant Cancer Cells in Breast Cancer." bioRxiv. 2024 Sep 24:2024.09.23.614522 PMID: 39386568
- 2. De-Ping Wang, Fang-Ying Jiang, et al. "Crystal structure of RNA helicase from Saint Louis encephalitis virus and discovery of its inhibitors." Genes Dis. 2022 Jul 31;10(2):389-392. PMID: 37223502
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
| A1229 | Lansoprazole | H+,K+-ATPase inhibitor | Membrane Transporter/Ion Channel|Proton Pump | 103577-45-3 | CC1=C(C=CN=C1CS(=O)C2=NC3=CC=CC=C3N2)OCC(F)(F)F |
| A1903 | E 64d | Cysteine protease inhibitor | Proteases|Cathepsin | 88321-09-9 | CCOC(=O)C1C(O1)C(=O)NC(CC(C)C)C(=O)NCCC(C)C |
| A2149 | Bosutinib (SKI-606) | Potent Abl/Src kinases | TGF-β / Smad Signaling|Bcr-Abl | 380843-75-4 | CN1CCN(CC1)CCCOC2=C(C=C3C(=C2)N=CC(=C3NC4=CC(=C(C=C4Cl)Cl)OC)C#N)OC |
| A2574 | Aprotinin | Inhibitor of bovine pancreatic trypsin | Proteases|Serine Protease | 9087-70-1 | CC(O)=O.CC.CC.CCccC.[R].[P].[2H].[L].[E].[P].[P].[Y].[3H].[G].[KH].[R].[R].[Y].F.[Y].[*].[L].F.[V].[Y].[G].[G].[R].[KH].[R].N.N.F.[KH].S.[*].[2H].[R].[G].[G].[*].[KH].[*].[3H].C.[*].F.[P].[*].I.I.N.[Q].[3H].[M] |
| A3021 | GDC-0449 (Vismodegib) | Hedgehog antagonist,potent and selective | Stem Cell|Hedgehog | 879085-55-9 | CS(=O)(=O)C1=CC(=C(C=C1)C(=O)NC2=CC(=C(C=C2)Cl)C3=CC=CC=N3)Cl |
| A8701 | Mesoridazine Besylate | Phenothiazine dopamine receptor anatagonist | Others|Others | 32672-69-8 | O=S(C)C1=CC=C2SC3=CC=CC=C3N(C2=C1)CC[C@H]4N(C)CCCC4.OS(=O)(C5=CC=CC=C5)=O |
| B1846 | Taurine | Glycine receptor agonist | Others|Others | 107-35-7 | C(CS(=O)(=O)O)N |
| C4910 | Spermine | Mixed NMDA glutamate receptor agonist/antagonist at the polyamine site | Neuroscience|NMDA | 71-44-3 | NCCCNCCCCNCCCN |
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
| Form | Pre-dissolved DMSO solutions | Stability | Solution: -20°C for 12 months, -80°C for 24 months |
| Packaging | 96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO). 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO). |
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| Shipping Condition | Evaluation sample solution: ship with blue ice All other available size: ship with RT, or blue ice upon request |
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