Fumonisin B1
Catalog No.
A4537
PP5/PP2Cα/PP2A/PP1γ2/PP2B inhibitor
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Mycotoxin produced by Fusarium moniliforme. Potently inhibits sphingosine N-acyltransferase (ceramide synthase), causing an accumulation of sphingoid bases (IC50 ~ 75 nM). Also inhibits protein phosphatases; IC50 values are 80, 300, 400, 500 and 3000 μM for PP5, PP2Cα, PP2A, PP1γ2 and PP2B respectively.
| Physical Appearance | A crystalline solid |
| Storage | Store at -20°C |
| M.Wt | 721.83 |
| Cas No. | 116355-83-0 |
| Formula | C34H59NO15 |
| Solubility | Limited solubility, soluble in DMSO |
| Chemical Name | rac-(2R,2'R)-2,2'-((((5S,6S,7R,9R,11S,16S,18R,19R)-19-amino-11,16,18-trihydroxy-5,9-dimethylicosane-6,7-diyl)bis(oxy))bis(2-oxoethane-2,1-diyl))disuccinic acid |
| SDF | Download SDF |
| Canonical SMILES | C[C@H](N)[C@@H](O)C[C@H](O)CCCC[C@@H](O)C[C@H](C)C[C@H](OC(C[C@@H](C(O)=O)CC(O)=O)=O)[C@H](OC(C[C@@H](C(O)=O)CC(O)=O)=O)[C@H](C)CCCC |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
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