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matrix protein (3-15) [Zaire ebolavirus]

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matrix protein (3-15) [Zaire ebolavirus]

matrix protein (3-15) [Zaire ebolavirus]

Catalog No.

A1080

Viral envelope associated protein peptide

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Grouped product items
Size	Price	Stock
1mg	$50.00	In stock
5mg	$150.00	In stock
10mg	$250.00	In stock
25mg	$350.00	In stock

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Background
Chemical Properties
Quality Control

Background

Matrix protein (3-15) is a peptide of the structure proteins linking the viral envelope with theZaireebolavirus core.

Ebola virus (EBOV) is a member of the family Filoviridae in the order Mononegavirales. It is the causative agent of severe hemorrhagic fevers in human and non-human primates with high case fatality rates.

A role for matrix proteins in the regulation of viral genome replication and transcription has been shown for a number of negative strand RNA viruses. The recent study has shown that both matrix proteins of EBOV, VP40 and VP24, are able to inhibit both viral genome replication and transcription.

A1080_1

Figure 1: Ribbon image of matrix protein VP40 of theZaire ebolavirus

Ref:

1. Hoenen T, Jung S, Herwig A, Groseth A, Becker S (2010) Both matrix proteins of Ebola virus contribute to the regulation of viral genome replication and transcription. Virology 403: 56–66.

2. Dessen A, Viktor V, Dolnik O, Klenk H, Weissenhorn W. Crystal structure of the matrix protein VP 40 from Ebola virus. The EMBO Journal (2010) 19, 4228-4236.

Chemical Properties

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	1515.77
Formula	C₆₉H₁₁₀N₁₆O₂₀S
Synonyms	H2N-Arg-Val-Ile-Leu-Pro-Thr-Ala-Pro-Pro-Glu-Tyr-Met-Glu-OH
Solubility	≥151.6 mg/mL in DMSO; insoluble in EtOH; ≥23.37 mg/mL in H2O
SDF	Download SDF
Canonical SMILES	NC(CCCNC(N)=N)C(NC(C(C)C)C(NC(C(C)CC)C(NC(CC(C)C)C(N(CCC1)C1C(NC(C(C)O)C(NC(C)C(N2CCCC2C(N3CCCC3C(NC(C(NC(CC4=CC=C(O)C=C4)C(NC(CCSC)C(NC(CCC(O)=O)C(O)=O)=O)=O)=O)CCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

Quality Control

Quality Control & MSDS

View current batch:

Purity = 98.14%

Chemical structure

matrix protein (3-15) [Zaire ebolavirus]

matrix protein (3-15) [Zaire ebolavirus]

mRNA synthesis

Tyramide Signal Amplification (TSA)

Phos Binding Reagent Acrylamide

Cell Counting Kit-8 (CCK-8)

Inhibitor Cocktails

Background

Chemical Properties

Quality Control

Quality Control & MSDS

Chemical structure

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