Mechlorethamine HCl
Catalog No.
B1785
DNA synthesis inhibitor
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Mechlorethamine is the prototype of alkylating agents, it works by binding to DNA, crosslinking two strands and preventing cell duplication.
- 1. Monika Witzenberger, Sandra Burczyk, et al. "Human TRMT2A methylates tRNA and contributes to translation fidelity." Nucleic Acids Res. 2023 Sep 8;51(16):8691-8710. PMID: 37395448
- 2. Witzenberger, Monika. "Multi-layered characterization of the tRNA methyltransferase TRMT2A and its therapeutic potential for polyQ diseases." University of Ulm. 2021.
| Physical Appearance | A solid |
| Storage | Store at -20°C |
| M.Wt | 192.51 |
| Cas No. | 55-86-7 |
| Formula | C5H11Cl2N·HCl |
| Solubility | ≥47.5 mg/mL in EtOH; ≥57.3 mg/mL in H2O; ≥9.65 mg/mL in DMSO |
| Chemical Name | 2-chloro-N-(2-chloroethyl)-N-methylethanamine;hydrochloride |
| SDF | Download SDF |
| Canonical SMILES | CN(CCCl)CCCl.Cl |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
