Mitraphylline
Catalog No.
A9072
Major pentacyclic oxindole alkaloid found in Uncaria tomentosa, inhibits lipopolysaccharide-induced activation of primary human neutrophils.
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Mitraphylline is the major pentacyclic oxindole alkaloid found in Uncaria tomentosa and exhibits both anti-inflammatory and antiproliferative properties. It reduces production of nitric oxide (NO), IL-8, IL-6, and TNF-a as well as expression of inducible nitric oxide synthase (iNOS) in LPS-activated human neutrophils.
| Storage | Store at 4°C away from moisture and light |
| M.Wt | 368.43 |
| Cas No. | 509-80-8 |
| Formula | C21H24N2O4 |
| Solubility | ≥9.13 mg/mL in DMSO; ≥2.83 mg/mL in EtOH with gentle warming and ultrasonic; insoluble in H2O |
| Chemical Name | methyl (1'S,3R,4a'S,5a'S,10a'R)-1'-methyl-2-oxo-4a',5',5a',7',8',10a'-hexahydro-1'H,10'H-spiro[indoline-3,6'-pyrano[3,4-f]indolizine]-4'-carboxylate |
| SDF | Download SDF |
| Canonical SMILES | O=C(OC)C1=CO[C@@H](C)[C@]2([H])[C@]1([H])C[C@]([C@]3(C(C=CC=C4)=C4NC3=O)CC5)([H])N5C2 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
