MK-4827 hydrochloride
Catalog No.
B1163
PARP1/PARP2 inhibitor
Featured Products
MK-4827(Niraparib) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.
Storage | Store at -20°C |
M.Wt | 356.85 |
Cas No. | 1038915-64-8 |
Formula | C19H21ClN4O |
Solubility | ≥23.7 mg/mL in DMSO; ≥20.85 mg/mL in EtOH; ≥41.7 mg/mL in H2O |
Chemical Name | 2-[4-[(3S)-piperidin-3-yl]phenyl]indazole-7-carboxamide;hydrochloride |
SDF | Download SDF |
Canonical SMILES | C1CC(CNC1)C2=CC=C(C=C2)N3C=C4C=CC=C(C4=N3)C(=O)N.Cl |
Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
