Mycoplasma Remover Reagent

Mycoplasmas are the smallest prokaryotic microorganism, only 0.1-0.3 μm in size. Due to their small size, mycoplasmas can penetrate rated filters (0.22~0.45 μm). Mycoplasma contamination remains a major problem in cell culture. Mycoplasmas can alter the DNA, RNA, and protein synthesis of culture cells, but they may not noticeably affect cell growth rates in many cases. Therefore, it is difficult to discover mycoplasma contamination with the naked eye. And it is a must to detect mycoplasma contamination routinely for laboratories that use cell culture frequently.

Mycoplasma Remover Reagent is a kind of natural antibiotic, which can effectively against various mycoplasmas species including Mycoplasma orale, Mycoplasma arginine, Mycoplasma hyorhinis, and Acholeplasma laidlawii. Mycoplasma Remover Reagent is very easy to use and has no toxicity to cell growth. Following treatment with Mycoplasma Remover Reagent for 2-3 weeks, mycoplasma contamination should be inhibited or eliminated.

Mycoplasma Remover Reagent is light yellow, soluble in water, and its solubility in water is approximately 15 mg/mL. The working concentration of this reagent for inhibiting mycoplasmas ranges from 0.01-0.5 μg/mL, and the working concentration for eliminating mycoplasmas ranges from 0.5-250 μg/ml. The most commonly used concentration ranges from 1-50 μg/mL. The working concentration of the reagent can be adjusted in different experiments.