Concanavalin A Magnetic Beads
Concanavalin A (ConA) is a plant mannose/glucose-binding lectin isolated from the seeds of cereal plants such as giant bean (Jack bean, Canavalia ensiformis), rice, bean, wheat, etc., and its monomer can bind one Ca2+ and one Mn2+ which Contains a glycosyl-binding site with high affinity for terminal α-D-mannosyl and α-D-glucosyl residues.
Concanavalin A Magnetic Beads (Canoladin A magnetic beads) is covalently coupled with canadolin A and superparamagnetic nanoscale magnetic beads, which can quickly, efficiently, sensitively and specifically bind to glycoproteins, glycolipids, polysaccharides and other glycosylation modification molecules, mainly used to isolate cells or for isolation of cell or tissue lysate or glycoprotein in serum glycosylation modification molecules and other experiments, as well as nuclease-targeted cleavage and release of chromatin (Cleavage Under Targets & Release Using Nuclease, CUT&RUN)。
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Characteristics |
Description |
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Product content |
10 mg/mL magnetic beads in specific protective buffer |
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Beads size |
~1 μm |
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Magnetization |
Superparamagnetic |
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Coupled protein |
Concanavalin A |
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M.W. of protein |
~102 kDa (tetramer) |
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Specificity |
Glycan and glycoconjugates |
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Application |
Isolating cells or glycoproteins, CUT&RUN |
Table The main related indicators of Concanavalin A Magnetic Beads.
- 1. Yun Xia, Xin Li, et al. "A method for predicting drugs that can boost the efficacy of immune checkpoint blockade." Nat Immunol. 2024 Apr;25(4):659-670. PMID: 38499799
- 2. Chen Wan, † Hui Zhang, et al. "Selective autophagy regulates chloroplast protein import and promotes plant stress tolerance." EMBO J. 2023 Jul; 42(14): e112534. PMID: 37248861
| Components | K1308-1 mL | K1308-5 mL |
| Concanavalin A Magnetic Beads | 1 mL | 5x1 mL |
Store the components dry at 4 °C for 12-18 months. | ||