RMC-6236
Catalog No.
A9992
A novel and highly effective inhibitor of RAS(ON) MULTI
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Rsc-6236 (Compound A122) is a novel and highly effective inhibitor of RAS(ON) MULTI. RAS proteins are frequently mutated and continuously activated in a variety of cancers, driving the proliferation and survival of tumor cells. RMC-6236 effectively blocks downstream signaling pathways by specifically binding to and inhibiting the active form of RAS protein (RAS(ON)), thereby inhibiting the growth and spread of cancer cells. Studies have shown that RCAC-6236 exhibits significant antitumor activity in a variety of cancer models, particularly for cancer types carrying RAS mutations, such as lung, pancreatic, and colorectal cancers.
| Storage | Store at -20°C for 3 years. |
| M.Wt | 811.06 |
| Cas No. | 2765081-21-6 |
| Formula | C44H58N8O5S |
| Solubility | Soluble in DMSO |
| Chemical Name | (1S,2S)-N-((63S,4S,Z)-11-ethyl-12-(2-((S)-1-methoxyethyl)-5-(4-methylpiperazin-1-yl)pyridin-3-yl)-10,10-dimethyl-5,7-dioxo-61,62,63,64,65,66-hexahydro-11H-8-oxa-2(4,2)-thiazola-1(5,3)-indola-6(1,3)-pyridazinacycloundecaphane-4-yl)-2-methylcyclopropane-1- |
| SDF | Download SDF |
| Canonical SMILES | O=C(OCC(C)(C)CC1=[C@@]([C@@]2=C([C@@H](OC)C)N=CC(N3CCN(C)CC3)=C2)N(CC)C4=C1C=C5C=C4)[C@@H]6CCCN(C([C@@H](NC([C@H]7C[C@@H]7C)=O)CC8=NC5=CS8)=O)N6 |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
- View current batch:
-
Purity = 98.00%
- COA (Certificate Of Analysis)
- MSDS (Material Safety Data Sheet)
Chemical structure
