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EGFR

EGFR (epidermal growth factor receptor) is the cell-surface receptor of its specific ligands, including epidermal growth factor and TGFα (transforming growth factor α) and is a receptor tyrosine kinase.

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  1. Compound 56
    A8197 Compound 56
     1 Citation
    Target: EGFR
    Summary: REGFR inhibitor
      insoluble in H2O; ≥16.95 mg/mL
  2. PD153035 hydrochloride
    A8199 PD153035 hydrochloride
     1 Citation
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; insoluble in H2O; ≥3.97 mg/mL
  3. CUDC-101
    A4092 CUDC-101
     1 Citation
    Target: Histone Deacetylases (HDACs)|EGFR|ErbB
    Summary: Multitargeted HDAC inhibitor
      ≥21.7 mg/mL
  4. AG-490
    A4139 AG-490
     3 Citation
    Target: EGFR|JAK
    Summary: JAK2/EGFR inhibitor
      insoluble in H2O; ≥14.7 mg/mL
  5. BMS-690514
    A3256 BMS-690514
    Summary: HER/EGFR inhibitor
      Soluble in DMSO
  6. CO-1686 (AVL-301)
    A3320 CO-1686 (AVL-301)
     1 Citation
    Target: EGFR
    Summary: EGFR inhibitor
      ≥27.8 mg/mL
  7. Erlotinib
    A3397 Erlotinib
     4 Citation
    Summary: EGFR tyrosine kinase inhibitor
      insoluble in H2O; ≥19.65 mg/mL
  8. Gefitinib hydrochloride
    A3433 Gefitinib hydrochloride
    Target: EGFR
    Summary: Potent EGFR inhibitor
      insoluble in EtOH; ≥4.28 mg/mL
  9. Icotinib Hydrochloride
    A3482 Icotinib Hydrochloride
    Summary: EGFR inhibitor,potent and specific
      Soluble in DMSO
  10. Lapatinib Ditosylate
    A3967 Lapatinib Ditosylate
    Target: EGFR|ErbB-2
    Summary: EGFR/HER2 inhibitor,potent and selective
      ≥24.3 mg/mL

Items 1-10 of 41

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