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PDE

PDE (phosphodiesterases) catalyze the hydrolysis of cGMP and/or cAMP. Stimulus such as light, neurotransmitter and hormone trigger PDE to regulate various biological response including vascular smooth muscle proliferation/contraction, hormone secretion and plate aggregation etc.

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  1. Vinpocetine
    B2276 Vinpocetine
    Target: Phosphodiesterases (PDEs)
    Summary: PDE inhibitor
      ≥2.59 mg/mL
  2. Amino Tadalafil
    C3266 Amino Tadalafil
    Summary: analog of tadalafil, a potent inhibitor of phosphodiesterase 5
      ≥57.4 mg/mL
  3. MBCQ
    C3510 MBCQ
    Summary: cGMP-specific phosphodiesterase PDE V inhibitor
      Soluble in DMSO
  4. Eggmanone
    C4796 Eggmanone
    Summary: selective inhibitor of PDE4
      ≤0.5 mg/mL
  5. 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide
    C4686 2-Acetamidophenyl 5-chloro-2-nitrophenyl sulfide
    Summary: phosphodiesterase 7 (PDE7) inhibitor
      ≤5 mg/mL
  6. ML-030
    C4805 ML-030
    Summary: PDE4 inhibitor
      ≤5 mg/mL
  7. Sp-Cyclic AMPS (sodium salt)
    C4942 Sp-Cyclic AMPS (sodium salt)
    Summary: cAMP derivative used to bind PDE10 GAF domain
      ≤25 mg/mL
  8. Ibudilast
    C5183 Ibudilast
    Summary: inhibitor of PDE4
  9. Milrinone
    B1386 Milrinone
    Target: Phosphodiesterases (PDEs)
    Summary: PDE-3 inhibitor
      insoluble in H2O; insoluble in EtOH; ≥8.2 mg/mL
  10. Pimobendan hydrochloride
    B1165 Pimobendan hydrochloride
    Summary: Selective inhibitor of PDE3
      Soluble in DMSO

Items 1-10 of 55

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