EDTA
EDTA (also known as edetic acid or etheylenediaminetetraacetic acid) is a chelating agent that binds certain metal ions (e.g. lead, calcium, magnesium and iron). EDTA has a variety of applications in laboratory, including preventing blood samples from clotting, keeping bacteria from forming a biofilm (thin layer stuck to a surface), as well as eliminating contaminating divalent cations and inhibiting protease activity in the process of protein purification. In addition, EDTA has also been applied in chelation therapy, acting by binding certain heavy metals and minerals such as lead and calcium and removing them from the body.
References:
1. Definition of EDTA - NCI Dictionary of Cancer Terms. National Cancer Institute. Retrieved 28 August 2021.
2. Mónico A, Martínez-Senra E, Cañada FJ, et al. Drawbacks of Dialysis Procedures for Removal of EDTA. PLoS One, 2017, 12(1): e0169843.
- 1. Yanzhuo Zhang, Zhe Lv, et al. "PIN1 Protects Hair Cells and Auditory HEI-OC1 Cells against Senescence by Inhibiting the PI3K/Akt/mTOR Pathway." Oxid Med Cell Longev. 2021 Jun 2;2021:9980444. PMID: 34285767
- 2. Wang K, Liao M, et al. "Parabacteroides distasonis Alleviates Obesity and Metabolic Dysfunctions via Production of Succinate and Secondary Bile Acids." Cell Rep. 2019 Jan 2;26(1):222-235.e5. PMID: 30605678
| Physical Appearance | A solid |
| Storage | Store at RT |
| M.Wt | 292.24 |
| Cas No. | 60-00-4 |
| Formula | C10H16N2O8 |
| Solubility | insoluble in EtOH; insoluble in DMSO; insoluble in H2O |
| Chemical Name | 2,2',2'',2'''-(ethane-1,2-diylbis(azanetriyl))tetraacetic acid |
| SDF | Download SDF |
| Canonical SMILES | OC(CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O)=O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | We do not recommend long-term storage for the solution, please use it up soon. |
Quality Control & MSDS
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Chemical structure
