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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Mouse complement C5a is a 77-amino acid peptide and is generated during complement activation from the α-chain of complement C5. Its molecular mass is 9 kDa. Mouse C5a shares 60% and 82% amino acid sequence identity to human C5a and rat C5a, respectively. Mouse C5a binds to a signaling G-protein coupled receptor (GPCR). It also triggers an oxidative burst in neutrophils and macrophages, and induces release of histamine in mast cells and basophils. C5a is necessary to the early priming stages of hepatocyte regeneration. Interception of C5a receptor signaling resulted in inhibiting of IL-6/TNFα induction and lack of C5a and C3 receptor stimulation attenuated nuclear factor–κB/STAT-3 activation after hepatectomy. The 9 kDa mouse C5a protein expressed in E. coli has a N-terminal his-tag sequence.