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In vitro transcription of capped mRNA with modified nucleotides and Poly(A) tail
TSA (Tyramide Signal Amplification), used for signal amplification of ISH, IHC and IC etc.
Separation of phosphorylated and non-phosphorylated proteins without phospho-specific antibody
A convenient and sensitive way for cell proliferation assay and cytotoxicity assay
Protect the integrity of proteins from multiple proteases and phosphatases for different applications.
Dibucaine is an amin amide local anesthetic [1].
Dibucaine has shown the ability to block the fast axonal transport of proteins. In addition, a 0.5 mM concentration of Dibucaine has been revealed to inhibit transport approximately as much as dose a 1mM concentration of tetracaine. Furthermore, 1mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 92%, and 0.5mM concentration of Dibucaine has been reported to reduce the radioactivity at the ligature by 72% in the experiments examined the effect on fast axonal transport of 3H-proteins [1].
References:[1] Lavoie PA. Block of fast axonal transport in vitro by the local anesthetics dibucaine and etidocaine. J Pharmacol Exp Ther. 1982 Oct;223(1):251-6.