DiscoveryProbe™ Protease Inhibitor Library
Catalog No.
L1035
A unique collection of 825 protease inhibitors for high throughput screening (HTS) and high content screening (HCS).
Featured Products
- 1. Sebastjan Kralj, Marko Jukič, et al. "Commercial SARS-CoV-2 Targeted, Protease Inhibitor Focused and Protein-Protein Interaction Inhibitor Focused Molecular Libraries for Virtual Screening and Drug Design." Int J Mol Sci. 2021 Dec 30;23(1):393. PMID: 35008818
- 2. Tenghua Wang, Wenxiu Ye, et al. "Protease Inhibitor-Dependent Inhibition of Light-Induced Stomatal Opening." Front Plant Sci. 2021 Sep 10;12:735328. PMID: 34567048
- 3. Huang L, Li L, et al. "Targeting HIV-1 Protease Autoprocessing for High-throughput Drug Discovery and Drug Resistance Assessment." Sci Rep. 2019 Jan 22;9(1):301. PMID: 30670786
| Catalog No. | Product Name | Summary | Targets | CAS Number | Smiles |
| A2576 | E-64 | Cysteine protease inhibitor,irriversible | Cathepsin | 66701-25-5 | CC(C)CC(C(=O)NCCCCN=C(N)N)NC(=O)C1C(O1)C(=O)O |
| A2606 | Epoxomicin | Proteasome inhibitor | Proteasome | 134381-21-8 | CCC(C)C(C(=O)NC(C(C)O)C(=O)NC(CC(C)C)C(=O)C1(CO1)C)NC(=O)C(C(C)CC)N(C)C(=O)C |
| A4018 | YO-01027 (Dibenzazepine, DBZ) | γ-secretase inhibitor | Gamma Secretase | 209984-56-5 | CC(C(=O)NC1C2=CC=CC=C2C3=CC=CC=C3N(C1=O)C)NC(=O)CC4=CC(=CC(=C4)F)F |
| A4054 | 17-AAG (KOS953) | Hsp90 inhibitor | HSP | 75747-14-7 | CC1CC(C(C(C=C(C(C(C=CC=C(C(=O)NC2=CC(=O)C(=C(C1)C2=O)NCC=C)C)OC)OC(=O)N)C)C)O)OC |
| A8200 | DAPT (GSI-IX) | γ-secretase inhibitor,potent and specific | Amyloid β | 208255-80-5 | CC(C(=O)NC(C1=CC=CC=C1)C(=O)OC(C)(C)C)NC(=O)CC2=CC(=CC(=C2)F)F |
| A8203 | Ritonavir | HIV protease inhibitor | HIV Protease | 155213-67-5 | CC(C)C1=NC(=CS1)CN(C)C(=O)NC(C(C)C)C(=O)NC(CC2=CC=CC=C2)CC(C(CC3=CC=CC=C3)NC(=O)OCC4=CN=CS4)O |
| A8206 | Darunavir | HIV-1 protease inhibitor | HIV Protease | 635728-49-3 | CCO.CC(C)CN(CC(C(CC1=CC=CC=C1)NC(=O)OC2COC3C2CCO3)O)S(=O)(=O)C4=CC=C(C=C4)N |
| A8239 | CA-074 Me | Cathepsin B inhibitor | Cathepsin | 147859-80-1 | CCCNC(=O)C1C(O1)C(=O)NC(C(C)CC)C(=O)N2CCCC2C(=O)OC |
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
Related Biological Data
| Form | Pre-dissolved DMSO solutions | Stability | Solution: -20°C for 12 months, -80°C for 24 months |
| Packaging | 96-well rack with Matrix 2D Barcoded ScrewTop Storage tubes (250 μL or 100 μL/well, 10 mM DMSO). 96-well DeepWell format with peelable foil seal and EVA cap (100 μL/well, 10 mM DMSO). |
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| Shipping Condition | Evaluation sample solution: ship with blue ice All other available size: ship with RT, or blue ice upon request |
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-- Available in stock with overnight delivery and free shipping over $500.
-- Cost-effective and competitive price to save your budget.
-- Potent, selective and cell-permeable in inhibiting or activating target molecules.
-- Diverse in chemical structure and route of administration (oral/i.m/i.v injection etc.)
-- Detailed files describing potency, selectivity and applications etc.
-- Supported by published data from top peer-reviewed journals.
-- Guaranteed high quality with NMR and HPLC validation.
